Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797008 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5800528 | 0.89 | PTGS2 (0.47) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5800526 | 0.89 | PTGS2 (0.47) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5797009 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL6425088 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1SLC6A3ALOX5 | |
| SCHEMBL6425175 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1SLC6A3ALOX5 | |
| SCHEMBL5800804 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1SLC6A3ALOX5 | |
| SCHEMBL5808091 | 0.88 | AKR1C3 (0.42) | PTGS2PTGS1ELANE | |
| SCHEMBL5797216 | 0.87 | PTGS2 (0.44) | PTGS2PTGS1APP | |
| SCHEMBL5547111 | 0.86 | PTGS2 (0.50) | PTGS2PTGS1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |