Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 8/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237138 | 0.82 | MAPK13 (0.57) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL5808420 | 0.76 | MAPK11 (0.54) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL5809579 | 0.76 | MAPK11 (0.49) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL5812461 | 0.76 | MAPK11 (0.51) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL5812295 | 0.76 | MAPK13 (0.53) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL4242576 | 0.75 | MAPK13 (0.69) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL4236992 | 0.74 | MAPK13 (0.71) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL5806880 | 0.74 | MAPK13 (0.50) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL5799317 | 0.74 | MAPK13 (0.70) | MAPK11MAPK13CYP2C9MAPK14MAPK12 | |
| SCHEMBL4247658 | 0.74 | MAPK11 (0.67) | MAPK11MAPK13CYP2C9MAPK14MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |