SCHEMBL5811976

SCHEMBL5811976

NC1(Cc2ccccc2)CC1Cl

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 15/20 0.61
MAOA P21397 13/20 0.61
MAOB P27338 13/20 0.61
RCOR1 Q9UKL0 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15767316 0.76 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL22335134 0.76 MAOA (0.58) KDM1AMAOAMAOBRCOR1
SCHEMBL18952159 0.76 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767973 0.76 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767612 0.76 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767610 0.76 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767315 0.76 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767992 0.75 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767605 0.75 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767602 0.75 KDM1A (1.00) KDM1AMAOAMAOBRCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006021403-A1 BICYCLONONENE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2006-03-02 WO disclosed