Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL29790549 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL5634201 | 0.83 | RAB9A (0.40) | ALDH1A1MMP1MMP3SMN1; SMN2HPGD | |
| SCHEMBL14511334 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL1363949 | 0.76 | — | — | |
| SCHEMBL2778162 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL23963672 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL4129583 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL8364865 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL7749269 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL5457 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103527-A1 | AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-05 | — | — | WO | disclosed |