SCHEMBL581305

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL581031	0.77	AURKA (0.63)	MEN1KMT2AAURKAAURKB
	SCHEMBL20406756	0.76	BRD4 (0.43)	MEN1KMT2AAURKAAURKBPDE10A
	SCHEMBL2460533	0.74	KMT2A (0.56)	MEN1KMT2AAPAF1TEAD4
	SCHEMBL2455636	0.73	PDE10A (0.58)	MEN1KMT2AAPAF1PDE10A
	SCHEMBL7904646	0.73	NCOA1 (0.58)	MEN1KMT2AAPAF1PDE10A
	SCHEMBL2456284	0.72	PDE10A (0.56)	MEN1KMT2AAPAF1PDE10A
	SCHEMBL580670	0.70	MEN1 (0.45)	MEN1KMT2AAPAF1PDE10A
	SCHEMBL20394339	0.69	BRD4 (0.40)	AURKAAURKB
	SCHEMBL8515345	0.69	MEN1 (0.58)	MEN1KMT2AAPAF1TEAD4
	SCHEMBL7898425	0.69	PDE10A (0.56)	MEN1KMT2AAPAF1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.