SCHEMBL5813239

SCHEMBL5813239

CCC(=O)c1ccc(SC)cc1N1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.45
PAX8 Q06710 1/20 0.45
KDM4E B2RXH2 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NPC1 O15118 3/20 0.43
ALDH1A1 P00352 6/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
KDM1A O60341 1/20 0.40
PRKDC P78527 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL501560 0.77 LMNA (0.53) KDM4EHSD17B10NPC1ALDH1A1SMN1; SMN2
SCHEMBL3931220 0.77 SMN1; SMN2 (0.56) RAB9APAX8KDM4EHSD17B10ALDH1A1
SCHEMBL28468862 0.73 ALDH1A1 (0.44) RAB9APAX8KDM4EHSD17B10ALDH1A1
SCHEMBL5063514 0.71 PRKDC (0.72) RAB9AKDM4EALDH1A1MAPTHTT
SCHEMBL316319 0.71 ALDH1A1 (0.48) RAB9APAX8HSD17B10ALDH1A1SMN1; SMN2
SCHEMBL2223630 0.71 ALDH1A1 (0.52) RAB9AHSD17B10NPC1ALDH1A1SMN1; SMN2
SCHEMBL28640009 0.71 ALDH1A1 (0.44) RAB9AKDM4ENPC1ALDH1A1SMN1; SMN2
SCHEMBL21951012 0.70 ALDH1A1 (0.65) RAB9AHSD17B10NPC1ALDH1A1SMN1; SMN2
SCHEMBL2257900 0.70 ALDH1A1 (0.45) RAB9AKDM4EHSD17B10NPC1ALDH1A1
SCHEMBL31229283 0.70 ALDH1A1 (0.45) RAB9AKDM4EHSD17B10NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006098424-A1 ANTIREFLECTION FILM, PRODUCTION METHOD THEREOF, POLARIZING PLATE USING THE ANTIREFLECTION FILM AND IMAGE DISPLAY DEVICE USING THE ANTIREFLECTION FILM OR POLARIZING PLATE FUJIFILM CORPORATION (JP) 2006-09-21 WO disclosed