Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813335 | 1.00 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5814404 | 0.91 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5814403 | 0.91 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5796532 | 0.90 | PTGS2 (0.42) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5799056 | 0.90 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5799060 | 0.90 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5800207 | 0.89 | PTGS2 (0.42) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5807298 | 0.88 | PTGS2 (0.41) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5800627 | 0.88 | PTGS2 (0.36) | PTGS2ESR1NR3C1PGRNR3C2 | |
| SCHEMBL5800622 | 0.88 | PTGS2 (0.36) | PTGS2ESR1NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |