Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800622 | 1.00 | PTGS2 (0.36) | PTGS2NR1H4ESR1NR3C1PGR | |
| SCHEMBL5809713 | 0.91 | PTGS2 (0.36) | PTGS2SLC22A12 | |
| SCHEMBL5809718 | 0.91 | PTGS2 (0.36) | PTGS2SLC22A12 | |
| SCHEMBL5559579 | 0.91 | PTGS2 (0.46) | PTGS2 | |
| SCHEMBL5559582 | 0.91 | PTGS2 (0.46) | PTGS2 | |
| SCHEMBL5814808 | 0.90 | MGLL (0.34) | PTGS2NR1H4MEN1KMT2A | |
| SCHEMBL5800716 | 0.90 | ALDH1A1 (0.36) | PTGS2NR1H4MEN1KMT2A | |
| SCHEMBL5800719 | 0.90 | ALDH1A1 (0.36) | PTGS2NR1H4MEN1KMT2A | |
| SCHEMBL5797307 | 0.89 | PTGS2 (0.36) | PTGS2SLC22A12 | |
| SCHEMBL5797301 | 0.89 | PTGS2 (0.36) | PTGS2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |