Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813350 | 1.00 | PTGS2 (0.34) | PTGS2TACR3TACR2TACR1MAOB | |
| SCHEMBL5797833 | 0.94 | PTGS2 (0.34) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5797831 | 0.94 | PTGS2 (0.34) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5800820 | 0.92 | PTGS2 (0.35) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5800822 | 0.92 | PTGS2 (0.35) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5813884 | 0.90 | PTGS2 (0.35) | PTGS2MAOBAKR1C3AKR1C2 | |
| SCHEMBL5813887 | 0.90 | PTGS2 (0.35) | PTGS2MAOBAKR1C3AKR1C2 | |
| SCHEMBL5822573 | 0.90 | APP (0.37) | PTGS2TACR3TACR2TACR1MAOB | |
| SCHEMBL5559956 | 0.89 | PTGS2 (0.38) | PTGS2TACR3TACR2TACR1MAOB | |
| SCHEMBL5562771 | 0.89 | PTGS2 (0.38) | PTGS2TACR3TACR2TACR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |