Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800820 | 1.00 | PTGS2 (0.35) | PTGS2MEN1KMT2ANR1H4ESR1 | |
| SCHEMBL5813347 | 0.92 | PTGS2 (0.34) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5813350 | 0.92 | PTGS2 (0.34) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5800314 | 0.91 | PTGS2 (0.32) | PTGS2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL5797831 | 0.90 | PTGS2 (0.34) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5797833 | 0.90 | PTGS2 (0.34) | PTGS2PTPN11AKR1C3AKR1C2 | |
| SCHEMBL5813216 | 0.90 | ALDH1A1 (0.35) | PTGS2MEN1KMT2ANR1H4AKR1C3 | |
| SCHEMBL5813215 | 0.90 | ALDH1A1 (0.35) | PTGS2MEN1KMT2ANR1H4AKR1C3 | |
| SCHEMBL5813477 | 0.89 | ELANE (0.35) | PTGS2MEN1KMT2ANR1H4CHRNA1 | |
| SCHEMBL5813474 | 0.89 | ELANE (0.35) | PTGS2MEN1KMT2ANR1H4CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |