Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756322 | 0.80 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL3817799 | 0.75 | CA12 (0.38) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL4756216 | 0.75 | LRRK2 (0.40) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL204727 | 0.74 | ALOX15 (0.64) | SMN1; SMN2NPC1RAB9AKMT2AHTT | |
| SCHEMBL9602642 | 0.74 | APP (0.46) | NPC1RAB9AKMT2AHTTLMNA | |
| SCHEMBL4754583 | 0.74 | KMT2A (0.49) | SMN1; SMN2KMT2AALDH1A1HTTLMNA | |
| SCHEMBL4700457 | 0.73 | LMNA (0.42) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL204996 | 0.73 | KDM4E (0.42) | SMN1; SMN2RAB9AALDH1A1HSD17B10USP5 | |
| SCHEMBL4759465 | 0.72 | POLB (0.45) | SMN1; SMN2KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4759468 | 0.71 | USP5 (0.44) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028451-A1 | 1-AMINO 1-H-IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |