Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557277 | 0.89 | ALDH1A1 (0.34) | ALDH1A1GAA | |
| SCHEMBL5818281 | 0.83 | MAPT (0.35) | ALDH1A1NPC1MAPTALOX15RAB9A | |
| SCHEMBL3573292 | 0.79 | TRPM8 (0.33) | ALDH1A1GAA | |
| SCHEMBL5813569 | 0.75 | ALDH1A1 (0.39) | ALDH1A1NPC1MAPTALOX15RAB9A | |
| SCHEMBL5813565 | 0.75 | ALDH1A1 (0.39) | ALDH1A1NPC1MAPTALOX15RAB9A | |
| SCHEMBL3569297 | 0.74 | CHRM2 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL3559263 | 0.74 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL3567401 | 0.69 | — | — | |
| SCHEMBL5819200 | 0.69 | ALDH1A1 (0.56) | ALDH1A1NPC1MAPTALOX15RAB9A | |
| SCHEMBL5813659 | 0.69 | ALDH1A1 (0.37) | ALDH1A1NPC1MAPTALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |