Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 7/20 | 0.57 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.57 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.57 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.57 |
| ▸ | RAF1 | P04049 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818421 | 0.91 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL6218709 | 0.91 | KCNH2 (0.65) | MAPK9RAF1KCNH2ACHE | |
| SCHEMBL5818632 | 0.91 | KCNH2 (0.65) | MAPK9RAF1KCNH2ACHE | |
| SCHEMBL6218705 | 0.91 | KCNH2 (0.65) | MAPK9RAF1KCNH2ACHE | |
| SCHEMBL5820631 | 0.90 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5816218 | 0.89 | MAPK9 (0.65) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5824185 | 0.86 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5819638 | 0.84 | KCNH2 (0.53) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5817342 | 0.84 | KCNH2 (0.59) | KCNH2ACHE | |
| SCHEMBL5823207 | 0.84 | MAPK14 (0.56) | MAPK13MAPK12MAPK11MAPK14MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |