Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177552 | 0.76 | AKT1 (0.42) | AKT1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL1173621 | 0.76 | AKT1 (0.42) | AKT1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL1274357 | 0.76 | AKT1 (0.42) | AKT1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL177551 | 0.76 | AKT1 (0.42) | AKT1TSHRTDP1POLBCYP3A4 | |
| SCHEMBL27514802 | 0.74 | BLM (0.46) | MAOAMAOBAKT1TSHRTDP1 | |
| SCHEMBL10419768 | 0.72 | MAOA (0.45) | MAOAMAOBAKT1TSHRTDP1 | |
| SCHEMBL1787995 | 0.72 | AKR1C1 (0.50) | MAOBAKT1TSHRPOLBMAPT | |
| SCHEMBL1787996 | 0.72 | AKR1C1 (0.50) | MAOBAKT1TSHRPOLBMAPT | |
| SCHEMBL3032149 | 0.72 | AKT1 (0.35) | MAOAMAOBAKT1TSHRTDP1 | |
| SCHEMBL646713 | 0.70 | MAOA (0.43) | MAOAMAOBAKT1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006094201-A2 | SEMICARBAZIDE-SENSITIVE AMIDE OXIDASE INHIBITORS | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |