Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177552 | 1.00 | AKT1 (0.42) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL1173621 | 0.78 | AKT1 (0.42) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL1274357 | 0.78 | AKT1 (0.42) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL27514802 | 0.76 | BLM (0.46) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL5813703 | 0.76 | MAOA (0.42) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL3937863 | 0.75 | ATM (0.40) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL3937865 | 0.75 | ATM (0.40) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL3940042 | 0.75 | ATM (0.40) | AKT1TSHRMAPTTDP1POLB | |
| SCHEMBL1787996 | 0.74 | AKR1C1 (0.50) | AKT1TSHRMAPTPOLBRECQL | |
| SCHEMBL1787995 | 0.74 | AKR1C1 (0.50) | AKT1TSHRMAPTPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-2792675-B1 | COMPOUND AND ASYMMETRIC SYNTHESIS REACTION | MICROBIAL CHEM RES FOUND (JP) | 2017-04-12 | — | — | EP | disclosed |
| CN-103998439-B | compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2016-03-23 | — | — | CN | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-9193716-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2015-11-24 | — | — | US | disclosed |
| US-9187498-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-11-17 | — | — | US | disclosed |
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEM RES FOUND (JP) | 2015-07-02 | — | — | US | disclosed |
| US-8981123-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-2792675-A1 | COMPOUND AND ASYMMETRIC SYNTHESIS REACTION | Microbial Chemistry Research Foundation (JP) | 2014-10-22 | — | — | EP | disclosed |
| WO-1993018006-A1 | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUED HYDROCARBONS | NARHEX LIMITED (HK) | 1993-09-16 | — | — | WO | disclosed |
| EP-0480242-A2 | Method for the production of alpha,beta-unsaturated carbonyl compounds | BASF Aktiengesellschaft (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0469423-A1 | Oxalyl-bishydroxamic acid derivatives, their preparation and plant growth regulating agents containing them | BASF Aktiengesellschaft (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5053070-A | PYRIMIDINE DERIVATIVES, PREPARATION PROCESSES THEREOF, HERBICIDE CONTAINING THE SAME, AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME ALONG WITH OTHER ACTIVE INGREDIENT | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-10-01 | — | — | US | disclosed |
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| US-4986846-A | PRE-AND POSTEMERGENCE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-01-22 | — | — | US | disclosed |
| CN-1043707-A | Pyrimidine derivatives and preparation method thereof and as herbicide applications | MITSUI TOATSU CHEMICALS (JP) | 1990-07-11 | — | — | CN | disclosed |
| EP-0374839-A1 | 2-(4,6-Dimethoxy-2-pyrimidinyloxy)benzaldoximes, preparation processes thereof, herbicides containing the same, and herbicidal compositions containing the same along with other active ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | AKT1 674/4885TSHR 354/4885MAPT 4096/4885 |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | AKT1 343/4885TSHR 2276/4885MAPT 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.