Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120646 | 0.97 | BCDIN3D (0.42) | BCDIN3DCHRM4PDE5AGAARXFP1 | |
| SCHEMBL7513169 | 0.94 | CHRM4 (0.40) | CHRM4PDE5AGAARXFP1PRKCI | |
| SCHEMBL7514448 | 0.92 | BCDIN3D (0.40) | BCDIN3DCHRM4PDE5A | |
| SCHEMBL5809508 | 0.91 | GAA (0.40) | CHRM4GAARXFP1PRKCI | |
| SCHEMBL5128434 | 0.90 | BCDIN3D (0.42) | BCDIN3DCHRM4PDE5A | |
| SCHEMBL5127812 | 0.89 | MEN1 (0.42) | CHRM4GAARXFP1PRKCI | |
| SCHEMBL5130870 | 0.87 | GAA (0.42) | CHRM4GAARXFP1PRKCI | |
| SCHEMBL5812974 | 0.86 | CHRM4 (0.40) | BCDIN3DCHRM4PDE5AGAA | |
| SCHEMBL5820926 | 0.85 | ALDH1A1 (0.44) | CHRM4PDE5AGAARXFP1PRKCI | |
| SCHEMBL5813640 | 0.84 | PRKCI (0.44) | PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685136-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047292-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2005-05-26 | — | — | WO | disclosed |