Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809461 | 1.00 | GAA (0.56) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5809244 | 0.88 | L3MBTL1 (0.69) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5809250 | 0.88 | L3MBTL1 (0.69) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5813681 | 0.87 | GAA (0.58) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5813671 | 0.87 | GAA (0.58) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5813205 | 0.86 | GAA (0.50) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5813192 | 0.86 | GAA (0.50) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5814381 | 0.78 | ALDH1A1 (0.54) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5809466 | 0.78 | ALDH1A1 (0.54) | GAAALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL5809423 | 0.76 | L3MBTL1 (0.65) | GAAALDH1A1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006136008-A1 | SALICYLIC ACID HYDRAZONES AS INHIBITORS OF THE ERK MAPKINASE PATHWAY AND FOR THE TREATMENT OF CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2006-12-28 | — | — | WO | disclosed |