Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671626 | 0.80 | HSD17B10 (0.65) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL10735538 | 0.80 | HSD17B10 (0.69) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL10729385 | 0.80 | HSD17B10 (0.65) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL10730206 | 0.79 | HSD17B10 (0.63) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL3627843 | 0.77 | HSD17B10 (0.66) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL10734727 | 0.77 | HSD17B10 (0.66) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL10730320 | 0.77 | HSD17B10 (0.61) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL5671154 | 0.77 | HSD17B10 (0.61) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL4328755 | 0.76 | HSD17B10 (1.00) | HSD17B10GLAHTTTSHRSMN1; SMN2 | |
| SCHEMBL5814643 | 0.76 | LMNA (0.55) | HSD17B10GLAHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |