Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.43 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993134 | 0.84 | LMNA (0.60) | LMNAMAPTSMN1; SMN2TP53HTT | |
| SCHEMBL7004061 | 0.82 | LMNA (0.58) | LMNAMAPTSMN1; SMN2TP53HTT | |
| SCHEMBL6997145 | 0.76 | SMN1; SMN2 (0.57) | LMNAMAPTSMN1; SMN2TP53NOX1 | |
| SCHEMBL5814733 | 0.76 | HSD17B10 (0.61) | MAPTSMN1; SMN2HTTHSD17B10ALDH1A1 | |
| SCHEMBL8523594 | 0.74 | LMNA (0.50) | LMNAMAPTSMN1; SMN2TP53HTT | |
| SCHEMBL6999115 | 0.70 | LMNA (0.47) | LMNAMAPTSMN1; SMN2TP53HTT | |
| SCHEMBL7000029 | 0.68 | LMNA (0.45) | LMNAMAPTSMN1; SMN2TP53HTT | |
| SCHEMBL7000067 | 0.66 | NOX1 (0.49) | LMNAMAPTSMN1; SMN2TP53HTT | |
| SCHEMBL6927126 | 0.66 | LMNA (0.42) | LMNAMAPTSMN1; SMN2TP53HTT | |
| SCHEMBL6755136 | 0.66 | SMN1; SMN2 (0.48) | LMNAMAPTSMN1; SMN2TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |