Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 3/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31265985 | 0.78 | IDH1 (0.49) | IDH1CALM1DAOCTRCSORT1 | |
| SCHEMBL596315 | 0.73 | CALM1 (0.50) | IDH1CALM1HSD17B10L3MBTL1LMNA | |
| SCHEMBL2116944 | 0.71 | — | — | |
| SCHEMBL4969798 | 0.71 | — | — | |
| SCHEMBL4701222 | 0.70 | NQO1 (0.48) | IDH1L3MBTL1NQO1GAA | |
| SCHEMBL27719076 | 0.69 | IDH1 (0.58) | IDH1CALM1DAOHSD17B10L3MBTL1 | |
| SCHEMBL31415070 | 0.69 | ALDH1A1 (0.43) | NQO1LMNAGAA | |
| SCHEMBL7145471 | 0.69 | — | — | |
| SCHEMBL11483794 | 0.69 | IDH1 (0.57) | IDH1CALM1DAOHSD17B10LMNA | |
| SCHEMBL1585486 | 0.69 | IDH1 (1.00) | IDH1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006039630-A2 | MATERIALS AND METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE THE CELL CYCLE | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2006-04-13 | — | — | WO | disclosed |