Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | IL6ST | P40189 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5992534 | 0.87 | OXER1 (0.47) | ALDH1A1MAPTRECQLOXER1KDM4E | |
| SCHEMBL28033575 | 0.85 | KMT2A (0.54) | ALDH1A1OXER1KDM4EL3MBTL1THRB | |
| SCHEMBL5742862 | 0.83 | OXER1 (0.41) | ALDH1A1MAPTRECQLOXER1KDM4E | |
| SCHEMBL2467334 | 0.83 | CDC25A (0.54) | ALDH1A1OXER1KDM4EL3MBTL1AKR1C3 | |
| SCHEMBL10442568 | 0.80 | OXER1 (0.56) | OXER1KDM4EFABP3FABP4FABP5 | |
| SCHEMBL5304010 | 0.80 | HTR2A (0.57) | ALDH1A1MAPTRECQLOXER1 | |
| SCHEMBL18423465 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTRECQLOXER1L3MBTL1 | |
| SCHEMBL351754 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTRECQLOXER1L3MBTL1 | |
| SCHEMBL11895393 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTRECQLOXER1L3MBTL1 | |
| SCHEMBL4518718 | 0.79 | STAT3 (0.42) | ALDH1A1MAPTRECQLOXER1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243135-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-12-03 | — | — | WO | disclosed |
| EP-2448939-B1 | 2,3-DIHYDRO-1H-IMIDAZO {1,2-A} PYRIMIDIN-5-ONE DERIVATIVES, THE PREPARATION AND PHARMACEUTICAL USE THEREOF | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |
| WO-2006061126-A2 | DIBENZOXAZEPINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-15 | — | — | WO | disclosed |