Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | KDR | P35968 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255828 | 0.83 | ALDH1A1 (0.64) | HDAC1HDAC2BLMALDH1A1KDM4E | |
| SCHEMBL5810496 | 0.81 | ABL1 (0.63) | ABL1PDGFRBHDAC3KDRHDAC4 | |
| SCHEMBL5815993 | 0.81 | ABL1 (0.66) | ABL1PDGFRBHDAC3KDRHDAC4 | |
| SCHEMBL5818898 | 0.81 | BLM (0.56) | ABL1PDGFRBHDAC3KDRHDAC4 | |
| SCHEMBL5816859 | 0.81 | HSD17B10 (0.46) | BLMALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5815495 | 0.76 | ABL1 (0.77) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL715436 | 0.75 | GAA (0.61) | ABL1PDGFRBHDAC3KDRHDAC4 | |
| SCHEMBL717068 | 0.72 | ABL1 (0.61) | ABL1PDGFRBHDAC3KDRHDAC4 | |
| SCHEMBL27911826 | 0.72 | ALDH1A1 (0.58) | HDAC1HDAC2BLMALDH1A1KDM4E | |
| SCHEMBL4832910 | 0.72 | GAA (0.64) | ABL1PDGFRBHDAC3KDRHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006064375-A9 | AMINOARYL SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES | AB SCIENCE (FR) | 2006-08-03 | — | — | WO | disclosed |