Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911826 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL2423069 | 0.85 | KDM4E (0.74) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL27911817 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8136410 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL5814903 | 0.83 | ABL1 (0.52) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL11008102 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10RAB9AHDAC1 | |
| SCHEMBL27821589 | 0.80 | RAB9A (0.58) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL23932950 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL1638585 | 0.80 | CDC7 (0.56) | ALDH1A1KDM4EHSD17B10SMN1; SMN2USP2 | |
| SCHEMBL27804580 | 0.78 | HDAC1 (0.68) | ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | ALDH1A1 1882/4885KDM4E 2988/4885HSD17B10 2001/4885 |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | ALDH1A1 1438/4885KDM4E 2511/4885HSD17B10 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.