Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580279 | 0.90 | EGFR (0.43) | EGFRHIF1AGAAKDM4EHSD17B10 | |
| SCHEMBL499950 | 0.80 | PPARA (0.63) | EGFRKDM4EALDH1A1TDP1PPARA | |
| SCHEMBL30473063 | 0.80 | PPARA (0.63) | EGFRKDM4EALDH1A1TDP1PPARA | |
| SCHEMBL3951791 | 0.78 | CFD (0.45) | EGFRGAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL580201 | 0.78 | EPHX2 (0.40) | EGFRGAAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3950219 | 0.77 | ALDH1A1 (0.38) | EGFRGAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL4299252 | 0.77 | KDM4C (0.37) | EGFRGAAKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL586740 | 0.76 | DTYMK (0.48) | EGFRGAASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL580967 | 0.76 | PPARA (0.57) | EGFRKDM4EHSD17B10ALDH1A1TDP1 | |
| SCHEMBL12800015 | 0.75 | POLB (0.51) | KDM4EHSD17B10SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417972-A2 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING BURN INJURIES | Neurotech Pharmaceuticals Co., Ltd. (KR) | 2012-02-15 | — | — | EP | claimed |