SCHEMBL581502

SCHEMBL581502

OCCCCCCCCCCCCCCCc1cc(O)ccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.50
TYR P14679 3/20 0.50
TP53 P04637 2/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 1/20 0.50
ALOX5 P09917 1/20 0.50
MAPT P10636 1/20 0.50
TSHR P16473 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
EGFR P00533 3/20 0.44
LCK P06239 1/20 0.44
IGF1R P08069 2/20 0.41
BCHE P06276 4/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580272 1.00 ALOX15 (0.50) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL586745 1.00 ALOX15 (0.50) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL9453919 1.00 ALOX15 (0.50) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL31596382 0.98 TYR (0.47) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL2987385 0.92 TYR (0.47) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL13065628 0.92 TYR (0.57) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL1846489 0.84 TYR (0.70) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL1467498 0.83 TYR (0.50) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL29434930 0.83 TYR (0.50) ALOX15TYRTP53CYP3A4MEN1
SCHEMBL23203418 0.82 TYR (0.49) ALOX15TYRTP53CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418191-A1 Long-chain trimethoxyphenylalkanol derivatives, and pharmaceuticals comprising the same Meiji Co., Ltd. (JP) 2012-02-15 EP disclosed
US-7893304-B2 Hydroquinone long-chain derivatives and/or phenoxy long-chain derivatives, and pharmaceuticals comprising the same MEIJI DAIRIES CORPORATION (JP) 2011-02-22 US disclosed
US-20090036542-A1 Hydroquinone Long-Chain Derivative and/or Phenoxy Long-Chain Derivative and Pharmaceutical Comprising Same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2009-02-05 US disclosed
EP-1854777-A1 HYDROQUINONE LONG-CHAIN DERIVATIVE AND/OR PHENOXY LONG-CHAIN DERIVATIVE, AND PHARMACEUTICAL PREPARATION COMPRISING THE SAME Meiji Dairies Corporation (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036542-A1 Hydroquinone Long-Chain Derivative and/or Phenoxy Long-Chain Derivative and Pharmaceutical Comprising Same NQO1, NDUFA10, UQCRC1 ALOX15 412/4885TYR 1225/4885TP53 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.