Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 4/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820442 | 0.92 | HRH3 (0.43) | AURKAAURKBCYP1A2NAMPTRIPK1 | |
| SCHEMBL5820856 | 0.92 | AURKA (0.41) | RAB9AAURKAAURKBCYP1A2NAMPT | |
| SCHEMBL5822993 | 0.91 | AURKA (0.42) | AURKAAURKBCYP1A2NAMPTRIPK1 | |
| SCHEMBL5820310 | 0.91 | HRH3 (0.45) | AURKAAURKBCYP1A2NAMPTRIPK1 | |
| SCHEMBL5821064 | 0.91 | SMN1; SMN2 (0.44) | RAB9AKMT2AMEN1NPC1HSD17B10 | |
| SCHEMBL5820813 | 0.91 | NAMPT (0.47) | RAB9AKMT2ANPC1AURKAAURKB | |
| SCHEMBL5820251 | 0.91 | CYP1A2 (0.45) | RAB9AKMT2AMEN1NPC1AURKA | |
| SCHEMBL5820606 | 0.91 | KDM4E (0.44) | RAB9ANPC1HSD17B10AURKAAURKB | |
| SCHEMBL5823039 | 0.90 | AURKA (0.50) | RAB9AKMT2ANPC1AURKAAURKB | |
| SCHEMBL5823980 | 0.90 | ZAP70 (0.49) | RAB9AKMT2ANPC1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137706-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM. CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |
| WO-2006137706-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM. CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |