Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820813 | 0.96 | NAMPT (0.47) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5820251 | 0.94 | CYP1A2 (0.45) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5816069 | 0.93 | AURKA (0.43) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5823980 | 0.93 | ZAP70 (0.49) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5821064 | 0.92 | SMN1; SMN2 (0.44) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5821823 | 0.91 | JAK3 (0.42) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5821753 | 0.91 | AURKA (0.45) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5815028 | 0.90 | RAB9A (0.46) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5820439 | 0.89 | NAMPT (0.44) | AURKANAMPTAURKBCYP1A2KMT2A | |
| SCHEMBL5823587 | 0.89 | JAK2 (0.43) | AURKANAMPTAURKBCYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137706-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM. CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |