Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MMP13 | P45452 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179085 | 0.87 | RAB9A (0.76) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL2937877 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL4991673 | 0.84 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL7322125 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL179082 | 0.84 | HPGD (0.73) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL20456560 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL29396735 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL179025 | 0.83 | HPGD (0.84) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL179079 | 0.83 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1GAAMEN1LMNA | |
| SCHEMBL109299 | 0.83 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1GAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101289483-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2012-06-20 | — | — | CN | disclosed |
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |