Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823064 | 0.78 | TACR1 (0.48) | SLC6A2SLC6A4SLC6A3CYP2D6MC4R | |
| SCHEMBL23632625 | 0.77 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL27906127 | 0.77 | SLC6A4 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6MC4R | |
| SCHEMBL27946025 | 0.76 | TACR1 (0.52) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5923826 | 0.75 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL6121889 | 0.74 | SLC6A3 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL2578935 | 0.73 | SLC6A4 (0.34) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5408143 | 0.72 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3CYP2D6ROCK2 | |
| SCHEMBL6557924 | 0.71 | MC4R (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6POLB | |
| SCHEMBL529996 | 0.71 | SLC6A4 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135383-A2 | INDAZOLES | MYRIAD GENETICS, INC. (US) | 2006-12-21 | — | — | WO | disclosed |