Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850350 | 0.84 | ABCB1 (0.41) | — | |
| Iodide SCHEMBL28776545 | 0.83 | ABCB1 (0.40) | — | |
| SCHEMBL1170553 | 0.79 | MTNR1B (0.43) | SLC18A2KCNH2 | |
| SCHEMBL27987674 | 0.79 | MTNR1B (0.43) | SLC18A2KCNH2 | |
| SCHEMBL581413 | 0.77 | MTNR1B (0.47) | SLC18A2KCNH2 | |
| SCHEMBL18535663 | 0.75 | DRD2 (0.31) | — | |
| SCHEMBL2691261 | 0.74 | SLC18A2 (0.70) | SLC18A2 | |
| M-Xylene SCHEMBL27492680 | 0.74 | MTNR1B (0.47) | SLC18A2KCNH2 | |
| SCHEMBL9963995 | 0.73 | SLC18A2 (0.68) | SLC18A2 | |
| SCHEMBL4515704 | 0.73 | HRH3 (0.47) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417131-A1 | ISOXAZOL-3(2H)-ONE ANALOGS AS THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117323-A1 | METHOD AND APPARATUS FOR PRODUCING HEAT ENERGY AND CARBON DIOXIDE | ASTRAZENECA AB (SE) | 2010-10-14 | — | — | WO | disclosed |