SCHEMBL581728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10271819	0.86	MAPT (0.48)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL2399730	0.82	AURKA (0.46)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL580459	0.75	ENPP3 (0.51)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL8021598	0.74	NPSR1 (0.79)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL7915123	0.74	KDR (0.70)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL15809924	0.73	AURKA (0.52)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL2209774	0.72	GAA (0.63)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL2210475	0.72	MAPT (0.56)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL7905055	0.71	NPSR1 (0.73)	ENPP3MAPTKDM4EALDH1A1PDE5A
	SCHEMBL7913355	0.71	GAA (0.66)	ENPP3MAPTKDM4EALDH1A1PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.