Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5814865 | 0.85 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5813643 | 0.83 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL5819600 | 0.83 | HTR1A (0.36) | HTR1AKCNH2 | |
| SCHEMBL5814293 | 0.82 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL18952772 | 0.80 | MAPT (0.40) | MAPT | |
| SCHEMBL5822655 | 0.80 | HRH3 (0.39) | MEN1KMT2AMAPTKCNH2 | |
| SCHEMBL5812990 | 0.79 | MEN1 (0.41) | MEN1KMT2APLAT | |
| SCHEMBL5815410 | 0.79 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL5819814 | 0.79 | GABRA1 (0.44) | MEN1KMT2AKCNH2 | |
| SCHEMBL5818833 | 0.78 | MEN1 (0.41) | MEN1KMT2APLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |