Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817915 | 0.87 | CDK2 (0.51) | ALDH1A1KDM4EMEN1GAAMAPK1 | |
| SCHEMBL5812677 | 0.86 | CDK2 (0.48) | ALDH1A1KDM4EMEN1GAAMAPK1 | |
| SCHEMBL5814889 | 0.85 | EGFR (0.45) | ALDH1A1KDM4EMEN1GAAMAPK1 | |
| SCHEMBL5818416 | 0.85 | CDK2 (0.47) | ALDH1A1KDM4EMEN1GAAMAPK1 | |
| SCHEMBL5819607 | 0.83 | KCNH2 (0.59) | KCNH2EGFR | |
| SCHEMBL5819555 | 0.83 | KMT2A (0.43) | ALDH1A1KDM4EMEN1GAAMAPK1 | |
| SCHEMBL5819605 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1GAAMAPK1 | |
| SCHEMBL5815854 | 0.78 | EGFR (0.62) | KCNH2EGFR | |
| SCHEMBL5819551 | 0.77 | KCNH2 (0.58) | KCNH2EGFR | |
| SCHEMBL5819446 | 0.77 | EGFR (0.51) | KCNH2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |