Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 6/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.51 |
| ▸ | KDM1A | O60341 | 6/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818320 | 0.92 | KDM1A (0.44) | ADRA1AADRA1BADRA1DKDM1AHTR1A | |
| Hydrochloric Acid SCHEMBL5821459 | 0.91 | KDM1A (0.44) | ADRA1AADRA1BADRA1DKDM1AHTR1A | |
| SCHEMBL5816386 | 0.89 | DRD2 (0.56) | ADRA1AADRA1BADRA1DKDM1AHTR1A | |
| SCHEMBL5809272 | 0.89 | KDM1A (0.63) | ADRA1AADRA1BADRA1DKDM1AHTR1A | |
| Hydrochloric Acid SCHEMBL5809295 | 0.88 | KDM1A (0.62) | ADRA1AADRA1BADRA1DKDM1AHTR1A | |
| SCHEMBL5821612 | 0.87 | KDM1A (0.53) | ADRA1AADRA1BADRA1DKDM1AHTR1A | |
| Hydrochloric Acid SCHEMBL5821923 | 0.86 | KDM1A (0.52) | ADRA1AADRA1BADRA1DKDM1AHTR1A | |
| SCHEMBL5816138 | 0.86 | DRD2 (0.52) | KDM1AHTR1A | |
| Hydrochloric Acid SCHEMBL5819949 | 0.85 | DRD2 (0.51) | ADRA1AKDM1AHTR1A | |
| SCHEMBL5821135 | 0.83 | KDM1A (0.46) | ADRA1AKDM1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |