Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5816094 | 0.99 | KDM1A (0.45) | KDM1AHTR1AHTR7DRD3LMNA | |
| SCHEMBL5807697 | 0.89 | KDM1A (0.57) | KDM1AHTR1AHTR7DRD3LMNA | |
| Hydrochloric Acid SCHEMBL5808304 | 0.88 | KDM1A (0.56) | KDM1AHTR1AHTR7DRD3LMNA | |
| SCHEMBL5816386 | 0.85 | DRD2 (0.56) | KDM1AHTR1AHTR7DRD3DRD2 | |
| SCHEMBL5821612 | 0.84 | KDM1A (0.53) | KDM1AHTR1AHTR7DRD3DRD2 | |
| SCHEMBL5817869 | 0.83 | ADRA1A (0.51) | KDM1AHTR1AADRA1A | |
| Hydrochloric Acid SCHEMBL5821923 | 0.83 | KDM1A (0.52) | KDM1AHTR1AHTR7DRD3DRD2 | |
| SCHEMBL5816138 | 0.82 | DRD2 (0.52) | KDM1AHTR1AHTR7DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL5819949 | 0.81 | DRD2 (0.51) | KDM1AHTR1AHTR7DRD3DRD2 | |
| SCHEMBL5809382 | 0.81 | KDM1A (0.50) | KDM1AHTR1AHTR7DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |