Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809689 | 0.79 | HDAC1 (0.43) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL1886656 | 0.75 | HDAC1 (0.62) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL1890495 | 0.75 | HDAC1 (0.62) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL8258701 | 0.75 | HDAC1 (0.75) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL1885626 | 0.71 | HDAC1 (0.87) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL8290259 | 0.71 | HDAC1 (0.74) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL1892231 | 0.70 | HDAC1 (0.85) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL8259238 | 0.70 | LMNA (0.44) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL8291934 | 0.70 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC2HDAC10 | |
| SCHEMBL1885021 | 0.70 | HDAC1 (0.83) | HDAC1HDAC3HDAC4HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | claimed |