Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1885021 | 0.93 | HDAC1 (0.83) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL5808344 | 0.91 | HDAC1 (0.61) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8259003 | 0.87 | HDAC1 (0.60) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1893680 | 0.86 | HDAC1 (1.00) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1895491 | 0.84 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL5805563 | 0.81 | HDAC1 (0.73) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8260320 | 0.81 | HDAC1 (0.67) | HDAC1NPC1RAB9A | |
| SCHEMBL8258697 | 0.81 | HDAC1 (0.63) | HDAC1 | |
| SCHEMBL8260770 | 0.80 | HDAC1 (0.63) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8256113 | 0.80 | HDAC1 (0.62) | HDAC1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |