Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063012 | 0.73 | TSHR (0.67) | PKMMAPTKDM4EKMT2AIDO1 | |
| SCHEMBL7116131 | 0.73 | TSHR (0.43) | ALOX15CYP3A4NFKB1PKMMAPT | |
| SCHEMBL5391085 | 0.73 | HIF1A (0.43) | ALOX15LMNAKDM4ETSHRHIF1A | |
| SCHEMBL8217518 | 0.72 | TAAR1 (0.52) | ALOX15CYP3A4NFKB1CYP1A2PKM | |
| Hydrochloric Acid SCHEMBL2115264 | 0.71 | TSHR (0.64) | PKMMAPTKDM4EKMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL5148250 | 0.71 | TSHR (0.64) | PKMMAPTKDM4EKMT2AIDO1 | |
| SCHEMBL633333 | 0.70 | ALDH1A1 (0.52) | ALOX15CYP3A4NFKB1CYP1A2MAPT | |
| SCHEMBL2993410 | 0.70 | MAOA (0.46) | CYP3A4CYP1A2MAPTKMT2AHIF1A | |
| SCHEMBL8223783 | 0.70 | TAAR1 (0.43) | ALOX15CYP3A4NFKB1CYP1A2PKM | |
| SCHEMBL28879973 | 0.70 | IDO1 (0.42) | ALOX15CYP3A4NFKB1CYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116184-A2 | METHODS AND COMPOSITIONS FOR CONTROLLING INVERTEBRATE PESTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-11-02 | — | — | WO | disclosed |