Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821574 | 0.93 | RARB (0.33) | RARBLMNA | |
| SCHEMBL700651 | 0.89 | RARB (0.36) | RARBLMNA | |
| SCHEMBL700556 | 0.81 | ALDH1A1 (0.33) | RARBLMNA | |
| SCHEMBL8857818 | 0.80 | LMNA (0.46) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL29008904 | 0.80 | LMNA (0.46) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11572956 | 0.80 | LMNA (0.46) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11790728 | 0.80 | LMNA (0.46) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL23666631 | 0.78 | LMNA (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL475375 | 0.78 | LMNA (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL398667 | 0.78 | LMNA (0.48) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130217-A2 | SUBSTITUTED PHOSPHATE ESTERS OF NUCLEOSIDE PHOSPHONATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-07 | — | — | WO | claimed |