Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979282 | 0.77 | S1PR5 (0.32) | S1PR1S1PR5 | |
| SCHEMBL1574943 | 0.76 | S1PR1 (0.31) | S1PR1S1PR5SGPL1 | |
| SCHEMBL2892210 | 0.75 | PDK2 (0.31) | S1PR1S1PR5 | |
| SCHEMBL1243209 | 0.73 | S1PR5 (0.34) | S1PR1S1PR5 | |
| SCHEMBL8932635 | 0.73 | FFAR4 (0.32) | S1PR1 | |
| SCHEMBL19433059 | 0.71 | EPHX1 (0.38) | EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19433025 | 0.71 | EPHX1 (0.38) | EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19446363 | 0.71 | EPHX1 (0.38) | EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2211595 | 0.71 | LMNA (0.32) | ALDH1A1KDM1A | |
| SCHEMBL5815956 | 0.70 | EPHX1 (0.37) | EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125550-A1 | METHOD FOR PRODUCING TETRAHYDROPYRANES FROM TETRAHYDROPYRAN-3-ONES | MERCK PATENT GMBH (DE) | 2006-11-30 | — | — | WO | disclosed |