SCHEMBL8932635

SCHEMBL8932635

CCCCCC1CCC(O)(c2ccc(-c3ccc(-c4ccc(OCC)c(F)c4F)cc3)cc2F)CC1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.32
NAAA Q02083 1/20 0.32
RARB P10826 2/20 0.31
RARA P10276 1/20 0.31
ESR2 Q92731 1/20 0.31
S1PR1 P21453 1/20 0.31
RARG P13631 1/20 0.30
ESR1 P03372 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30
TDP2 O95551 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8932601 0.93 FFAR4 (0.33) FFAR4NAAARARBS1PR1RARG
SCHEMBL8932660 0.87 FPR2 (0.31) FFAR4NAAA
SCHEMBL8932623 0.86 APP (0.35) FFAR4RARBESR1
SCHEMBL8932785 0.81 FFAR4 (0.38) FFAR4NAAAS1PR1
SCHEMBL8934124 0.81 OPRL1 (0.34) FFAR4NAAARARBRARA
SCHEMBL8969240 0.81 NAAA (0.39) FFAR4NAAARARBRARAESR2
SCHEMBL8934342 0.80 OPRL1 (0.34) FFAR4NAAARARBRARA
SCHEMBL8960881 0.78 OPRL1 (0.33) FFAR4NAAARARBRARA
SCHEMBL2892210 0.78 PDK2 (0.31) S1PR1
SCHEMBL8961187 0.77 FFAR4 (0.33) FFAR4NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE KIF23, HCN3, FZD7 FFAR4 342/4885NAAA 4128/4885RARB 3042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.