Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11188407 | 0.84 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL1520044 | 0.76 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL10571493 | 0.75 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL10575793 | 0.75 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL11115568 | 0.72 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL903215 | 0.72 | LMNA (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL10016350 | 0.71 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10573853 | 0.71 | KDM4E (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL8915226 | 0.71 | HSD17B10 (0.61) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL4870340 | 0.69 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |