Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819814 | 0.96 | GABRA1 (0.44) | GABRA1GABRB2HTR2CMAPK14KCNH2 | |
| SCHEMBL5819266 | 0.89 | KCNH2 (0.39) | GABRA1GABRB2KCNH2ACHE | |
| SCHEMBL5814885 | 0.88 | MAPK14 (0.40) | GABRA1GABRB2MAPK14KCNH2CNR1 | |
| SCHEMBL5813729 | 0.86 | MEN1 (0.42) | HTR2CMAPK14MEN1KMT2A | |
| SCHEMBL5814140 | 0.85 | GABRA1 (0.39) | GABRA1GABRB2HTR2CMAPK14KCNH2 | |
| SCHEMBL5813870 | 0.84 | MAPK14 (0.39) | GABRA1GABRB2MAPK14KCNH2 | |
| SCHEMBL5818833 | 0.83 | MEN1 (0.41) | HTR2CMAPK14MEN1KMT2A | |
| SCHEMBL5815410 | 0.82 | KCNH2 (0.47) | KCNH2ACHE | |
| SCHEMBL5812990 | 0.82 | MEN1 (0.41) | HTR2CMAPK14MEN1KMT2A | |
| SCHEMBL5814697 | 0.82 | MEN1 (0.38) | HTR2CKCNH2ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |