Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819500 | 0.96 | HTR2A (0.42) | MEN1KMT2AKCNH2HTR2AHTR2C | |
| SCHEMBL5815410 | 0.87 | KCNH2 (0.47) | KCNH2ACHE | |
| SCHEMBL5817154 | 0.84 | KMT2A (0.50) | KMT2AKCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL5813643 | 0.83 | KCNH2 (0.46) | KCNH2ACHE | |
| SCHEMBL5814293 | 0.83 | KCNH2 (0.46) | KCNH2ACHE | |
| SCHEMBL3096733 | 0.83 | KMT2A (0.49) | MEN1KMT2AKCNH2HTR2AHTR2C | |
| SCHEMBL5814865 | 0.82 | KCNH2 (0.45) | KCNH2ACHE | |
| SCHEMBL5818784 | 0.82 | GABRA1 (0.45) | MEN1KMT2AKCNH2HTR2CACHE | |
| SCHEMBL5817700 | 0.81 | KMT2A (0.48) | KMT2AKCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL5819266 | 0.80 | KCNH2 (0.39) | KCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |