Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35172 | 0.80 | HSD17B10 (0.55) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| SCHEMBL20163213 | 0.80 | HSD17B10 (0.55) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| Fluoride SCHEMBL20815438 | 0.78 | TAS2R38 (0.52) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| Hydrochloric Acid SCHEMBL5608654 | 0.78 | TAS2R38 (0.52) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| SCHEMBL31160596 | 0.78 | TAS2R38 (0.52) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| Bromide SCHEMBL473887 | 0.78 | TAS2R38 (0.52) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| SCHEMBL330186 | 0.76 | ALDH1A1 (0.64) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| SCHEMBL68444 | 0.76 | EPHX2 (0.64) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| SCHEMBL8791034 | 0.76 | TAS2R38 (0.50) | HSD17B10TAS2R38ALDH1A1TP53TSHR | |
| SCHEMBL1687694 | 0.76 | TAS2R38 (0.58) | HSD17B10TAS2R38ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |