Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816644 | 0.85 | HPGD (0.73) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL26125904 | 0.85 | ALDH1A1 (0.68) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL5819645 | 0.83 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7256405 | 0.82 | NPSR1 (0.79) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7252897 | 0.78 | HPGD (0.83) | MAPTALDH1A1SMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL7258078 | 0.75 | HPGD (0.83) | MAPTALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL13488596 | 0.74 | NPSR1 (0.66) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL14236103 | 0.73 | NPSR1 (0.70) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL17278348 | 0.72 | NPSR1 (0.63) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL16090202 | 0.69 | NPSR1 (0.59) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |