Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.79 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252897 | 0.87 | HPGD (0.83) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL7258078 | 0.87 | HPGD (0.83) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL14236103 | 0.86 | NPSR1 (0.70) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL26125904 | 0.83 | ALDH1A1 (0.68) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL12531935 | 0.83 | CYP1A2 (0.64) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL13488596 | 0.83 | NPSR1 (0.66) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL5819637 | 0.82 | MAPT (0.66) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL5819645 | 0.82 | MAPT (0.66) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL7252775 | 0.81 | KMT2A (0.66) | NPSR1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17278348 | 0.81 | NPSR1 (0.63) | NPSR1RAB9ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035614-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |
| US-6258959-B1 | NITROSATION AN ACETOACETATE; REDUCTION; CYCLIZATION | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| US-6166223-A | Process for the preparation of 2,4-dimethylpyrrole | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-1013646-A1 | Process for the Synthesis of 2,4-Dimethyl-3,5-bis-alkoxy-carbonyl-pyrrole | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |
| EP-1013645-A1 | Process for the preparation of 2,4-dimethyl-pyrrole | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-28 | — | — | EP | disclosed |