Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.44 |
| ▸ | SKP1 | P63208 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818457 | 0.92 | MAPK14 (0.47) | CKS1BSKP1SKP2MAPK1MAPK14 | |
| SCHEMBL5812519 | 0.87 | MAPK14 (0.44) | CKS1BSKP1SKP2MAPK14MAPK13 | |
| SCHEMBL5819533 | 0.87 | MAPK14 (0.43) | CKS1BSKP1SKP2ACHEMAPK14 | |
| SCHEMBL5818694 | 0.86 | CKS1B (0.39) | CKS1BSKP1SKP2IDH1MAPK1 | |
| SCHEMBL5816369 | 0.86 | CKS1B (0.41) | CKS1BSKP1SKP2ACHEPPARG | |
| SCHEMBL5819478 | 0.86 | MAPK14 (0.55) | CKS1BSKP1SKP2MAPK14MAPK13 | |
| SCHEMBL5819690 | 0.85 | ALDH1A1 (0.49) | KMT2AALDH1A1HTTNPSR1IDH1 | |
| SCHEMBL5813636 | 0.85 | ALDH1A1 (0.48) | CKS1BSKP1SKP2KMT2AALDH1A1 | |
| SCHEMBL5812762 | 0.85 | SLC2A1 (0.48) | CKS1BSKP1SKP2KMT2AALDH1A1 | |
| SCHEMBL5820567 | 0.84 | KCNH2 (0.50) | KMT2AIDH1MAPK1MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |