Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815367 | 0.88 | MAPK14 (0.45) | SLC2A1ACHECKS1BSKP1SKP2 | |
| SCHEMBL5819639 | 0.85 | CKS1B (0.44) | ACHETLR9KMT2ACKS1BSKP1 | |
| SCHEMBL5813636 | 0.84 | ALDH1A1 (0.48) | KMT2ACKS1BSKP1SKP2MAPT | |
| SCHEMBL5819074 | 0.83 | ALDH1A1 (0.47) | KMT2ACKS1BSKP1SKP2MAPT | |
| SCHEMBL5818673 | 0.82 | ALDH1A1 (0.46) | KMT2AMAPTALDH1A1HTTNPSR1 | |
| SCHEMBL5819327 | 0.80 | KMT2A (0.48) | KMT2ACKS1BSKP1SKP2MAPT | |
| SCHEMBL3100957 | 0.79 | KMT2A (0.64) | KMT2ACKS1BSKP1SKP2MAPT | |
| SCHEMBL5819400 | 0.79 | KMT2A (0.46) | KMT2ACKS1BSKP1SKP2MAPT | |
| SCHEMBL5818457 | 0.77 | MAPK14 (0.47) | CKS1BSKP1SKP2 | |
| SCHEMBL5812944 | 0.76 | KCNH2 (0.47) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |