Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819697 | 1.00 | KDM4E (0.34) | KDM4EHSP90AA1NPSR1ALDH1A1NPC1 | |
| SCHEMBL5822574 | 0.76 | ALDH1A1 (0.33) | KDM4EALDH1A1TSHR | |
| SCHEMBL5822579 | 0.76 | ALDH1A1 (0.33) | KDM4EALDH1A1TSHR | |
| SCHEMBL377078 | 0.74 | ESR1 (0.45) | KDM4EALDH1A1POLBKMT2AGLA | |
| SCHEMBL5819315 | 0.71 | MEN1 (0.33) | KDM4EKMT2A | |
| SCHEMBL11145996 | 0.69 | NPSR1 (0.42) | KDM4EHSP90AA1NPSR1ALDH1A1NPC1 | |
| SCHEMBL314578 | 0.66 | ALDH1A1 (0.52) | NPSR1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL6812066 | 0.64 | KDM4E (0.44) | KDM4EHSP90AA1NPSR1ALDH1A1NPC1 | |
| SCHEMBL5716541 | 0.64 | TSHR (0.50) | HSP90AA1ALDH1A1NPC1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL7930929 | 0.64 | ALDH1A1 (0.50) | NPSR1ALDH1A1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | claimed |